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Bacteriophage lambda major capsid protein mutant - W308A

Analyse Bacteriophage lambda major capsid protein mutant - W308A in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7SJ5
Type: protein
Length: 1,360 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Major capsid protein
UniProt: P03713
Pockets: 20 · best druggability 0.78

Structure

x-ray diffraction · 1 distinct chain · 31% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D	Major capsid protein	protein	340	31% helix, 27% strand	P03713

Pockets

20 pockets found on a 1 Å grid, 11 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1000	0.78	0.79	85	empty
2	1018	0.77	0.79	72	empty
3	863	0.77	0.80	67	empty
4	557	0.76	0.83	53	empty
5	642	0.75	0.81	58	empty

Interfaces

5 interfaces between chains.

A–C · 1559 Å² buried · 20 hydrogen bonds · protein-protein
A–B · 1504 Å² buried · 21 hydrogen bonds · protein-protein
C–D · 301 Å² buried · 2 hydrogen bonds · protein-protein
B–D · 284 Å² buried · 4 hydrogen bonds · protein-protein
A–D · 181 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

7SJ5 · Bacteriophage lambda major capsid protein mutant - W308A · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P03713
Elsewhere: RCSB PDB 7SJ5 · PDBe 7SJ5 · UniProt P03713

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