Research workbench
Structure of ATP7B in state 2
Analyse Structure of ATP7B in state 2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7SI7
- Type
- protein
- Length
- 728 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- P-type cu(+) transporter
- EC
- 7.2.2.8
- UniProt
- A0A6I8R0A5
- Ligands
- ALF, MG
- Pockets
- 11 · best druggability 0.72
Structure
electron microscopy · 1 distinct chain · 52% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | P-type cu(+) transporter (EC 7.2.2.8) | protein | 728 | 52% helix, 15% strand | A0A6I8R0A5 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
11 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 515 | 0.72 | 0.81 | 53 | empty |
| 2 | 647 | 0.71 | 0.79 | 64 | empty |
| 3 | 223 | 0.59 | 0.80 | 30 | empty |
| 4 | 169 | 0.47 | 0.76 | 27 | empty |
| 5 | 52 | 0.46 | 0.85 | 20 | empty |
Compared structures
- 7SI7 · Structure of ATP7B in state 2 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A6I8R0A5
- Elsewhere: RCSB PDB 7SI7 · PDBe 7SI7 · UniProt A0A6I8R0A5
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