Research workbench
TRNA-like structure from brome mosaic virus bound to tyrosyl-tRNA synthetase from phaseolus vulgaris. conformation: bound state 1.
Analyse TRNA-like structure from brome mosaic virus bound to tyrosyl-tRNA synthetase… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7SC6
- Type
- protein + RNA
- Length
- 867 residues
- Chains
- 3
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tyrosine--tRNA ligase; TRNA-like structure from brome mosaic virus RNA 3
- EC
- 6.1.1.1
- UniProt
- V7CJ18
- Pockets
- 12 · best druggability 0.79
Structure
electron microscopy · 2 distinct chains · 58% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Tyrosine--tRNA ligase (EC 6.1.1.1) | protein | 349 | 58% helix, 11% strand | V7CJ18 |
| C | TRNA-like structure from brome mosaic virus RNA 3 | rna | 169 | — | — |
Pockets
12 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 446 | 0.79 | 0.87 | 50 | empty |
| 2 | 433 | 0.75 | 0.85 | 39 | empty |
| 3 | 756 | 0.67 | 0.76 | 33 | empty |
| 4 | 649 | 0.61 | 0.74 | 32 | empty |
| 5 | 306 | 0.48 | 0.73 | 24 | empty |
Interfaces
3 interfaces between chains.
- A–B · 998 Ų buried · 3 hydrogen bonds · protein-protein
- A–C · 302 Ų buried · 4 hydrogen bonds · protein-nucleic
- B–C · 159 Ų buried · 3 hydrogen bonds · protein-nucleic
Compared structures
- 7SC6 · tRNA-like Structure from Brome Mosaic Virus Bound to Tyrosyl-tRNA Synthetase from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt V7CJ18
- Elsewhere: RCSB PDB 7SC6 · PDBe 7SC6 · UniProt V7CJ18
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.