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Tandem diubiquitin-like domain from chicken 2'-5'-oligoadenylate synthetase-like protein

Analyse Tandem diubiquitin-like domain from chicken 2'-5'-oligoadenylate… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
7SBI
Type
protein
Length
310 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
2'-5' oligoadenylate synthase
UniProt
O13255
Pockets
1 · best druggability 0.71

Structure

x-ray diffraction · 2 distinct chains · 23% helix, 34% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A2'-5' oligoadenylate synthaseprotein15423% helix, 34% strandO13255
B2'-5' oligoadenylate synthaseprotein15623% helix, 33% strandO13255

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
110010.710.7581empty

Interfaces

1 interface between chains.

  • A–B · 652 Ų buried · 4 hydrogen bonds · protein-protein

Compared structures

  • 7SBI · Tandem diubiquitin-like domain from chicken 2'-5'-oligoadenylate synthetase-like protein · the same entry in another collection · chain A against A, TM-score 1.00

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