Research workbench
Structure of porlm, the proton-powered motor that drives type IX protein secretion
Analyse Structure of porlm, the proton-powered motor that drives type IX protein… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7SAT
- Type
- protein
- Length
- 822 residues
- Chains
- 7
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Por secretion system protein PORM/GLDM; Por secretion system protein PORL/GLDL
- UniProt
- B2RLE8, B2RLE9
- Pockets
- 13 · best druggability 0.79
Structure
electron microscopy · 5 distinct chains · 66% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Por secretion system protein PORM/GLDM | protein | 219 | 63% helix, 0% strand | B2RLE8 |
| B | Por secretion system protein PORM/GLDM | protein | 218 | 64% helix, 0% strand | B2RLE8 |
| C, F, G | Por secretion system protein PORL/GLDL | protein | 77 | 78% helix, 0% strand | B2RLE9 |
| D | Por secretion system protein PORL/GLDL | protein | 74 | 68% helix, 0% strand | B2RLE9 |
| E | Por secretion system protein PORL/GLDL | protein | 80 | 69% helix, 0% strand | B2RLE9 |
Pockets
13 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1085 | 0.79 | 0.81 | 110 | empty |
| 2 | 603 | 0.72 | 0.80 | 58 | empty |
| 3 | 436 | 0.67 | 0.79 | 44 | empty |
| 4 | 167 | 0.59 | 0.83 | 23 | empty |
| 5 | 142 | 0.50 | 0.79 | 22 | empty |
Interfaces
16 interfaces between chains.
- A–B · 1898 Ų buried · 9 hydrogen bonds · protein-protein
- D–E · 957 Ų buried · 3 hydrogen bonds · protein-protein
- C–D · 920 Ų buried · 5 hydrogen bonds · protein-protein
- C–G · 909 Ų buried · 0 hydrogen bonds · protein-protein
- E–F · 894 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 7SAT · Structure of PorLM, the proton-powered motor that drives Type IX protein secretion · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B2RLE8
- Every structure of UniProt B2RLE9
- Elsewhere: RCSB PDB 7SAT · PDBe 7SAT · UniProt B2RLE8 · UniProt B2RLE9
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