Research workbench
Cryo-EM structure of dolphin prestin: sensor down I (expanded) state
Analyse Cryo-EM structure of dolphin prestin: sensor down I (expanded) state in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7S9B
- Type
- protein
- Length
- 1,356 residues
- Chains
- 2
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Prestin
- UniProt
- D7PC76
- Pockets
- 20 · best druggability 0.85
Structure
electron microscopy · 1 distinct chain · 56% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Prestin | protein | 678 | 56% helix, 4% strand | D7PC76 |
Pockets
20 pockets found on a 1 Å grid, 19 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 920 | 0.85 | 0.87 | 83 | empty |
| 2 | 1189 | 0.84 | 0.85 | 164 | empty |
| 3 | 890 | 0.81 | 0.83 | 129 | empty |
| 4 | 177 | 0.78 | 0.93 | 37 | empty |
| 5 | 64 | 0.72 | 0.97 | 23 | empty |
Interfaces
1 interface between chains.
- A–B · 3371 Ų buried · 42 hydrogen bonds · protein-protein
Compared structures
- 7S9B · Cryo-EM Structure of dolphin Prestin: Sensor Down I (Expanded) state · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D7PC76
- Elsewhere: RCSB PDB 7S9B · PDBe 7S9B · UniProt D7PC76
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