Research workbench

Structure of sortase a from streptococcus pyogenes with the B7-B8 loop sequence from listeria monocytogenes sortase a

Analyse Structure of sortase a from streptococcus pyogenes with the B7-B8 loop sequence… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7S53
Type: protein
Length: 157 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Class a sortase, sortase a chimera
EC: 3.4.22.-
UniProt: A0A4U7I1I9, Q8Y8H5
Pockets: 1 · best druggability 0.30

Structure

x-ray diffraction · 1 distinct chain · 20% helix, 38% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Class a sortase, sortase a chimera (EC 3.4.22.-)	protein	157	20% helix, 38% strand	A0A4U7I1I9, Q8Y8H5

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	56	0.30	0.75	19	empty

Compared structures

7S53 · Structure of Sortase A from Streptococcus pyogenes with the b7-b8 loop sequence from… · the same entry in another collection · chain A against A, TM-score 1.00
Q8Y8H5 · AlphaFold monomer V2.0 prediction for sortase a (Q8Y8H5) · a predicted model of the same protein · chain A against A, TM-score 0.86

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A4U7I1I9
Every structure of UniProt Q8Y8H5
Elsewhere: RCSB PDB 7S53 · PDBe 7S53 · UniProt A0A4U7I1I9 · UniProt Q8Y8H5

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.