Research workbench

Crystal structure of a complement factor H-binding fragment within the B75KN region of the group B streptococcus beta antigen C protein

Analyse Crystal structure of a complement factor H-binding fragment within the B75KN… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7S0R
Type: protein
Length: 167 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: C protein beta antigen
UniProt: Q3MUG3
Pockets: 1 · best druggability 0.34

Structure

x-ray diffraction · 2 distinct chains · 77% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	C protein beta antigen	protein	85	76% helix, 0% strand	Q3MUG3
B	C protein beta antigen	protein	82	78% helix, 0% strand	Q3MUG3

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	84	0.34	0.74	17	empty

Interfaces

1 interface between chains.

A–B · 888 Å² buried · 13 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 6 modified (engineered).

Compared structures

7S0R · Crystal Structure of a Complement Factor H-binding Fragment within the B75KN Region of… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q3MUG3
Elsewhere: RCSB PDB 7S0R · PDBe 7S0R · UniProt Q3MUG3

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.