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Crystal structure of penicillium verruculosum copalyl diphosphate synthase (pvcps) alpha prenyltransferase domain variant, F760A

Analyse Crystal structure of penicillium verruculosum copalyl diphosphate synthase… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7S09
Type: protein
Length: 597 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Terpene synthase
UniProt: A0A348FUE1
Pockets: 6 · best druggability 0.78

Structure

x-ray diffraction · 2 distinct chains · 71% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Terpene synthase	protein	301	70% helix, 1% strand	A0A348FUE1
B	Terpene synthase	protein	296	72% helix, 1% strand	A0A348FUE1

Pockets

6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	589	0.78	0.84	57	empty
2	100	0.77	0.97	17	empty
3	708	0.77	0.82	76	empty
4	130	0.44	0.77	26	empty
5	65	0.38	0.79	16	empty

Interfaces

1 interface between chains.

A–B · 2451 Å² buried · 25 hydrogen bonds · protein-protein

Compared structures

7S09 · Crystal structure of Penicillium verruculosum copalyl diphosphate synthase (PvCPS) alpha… · the same entry in another collection · chain A against A, TM-score 1.00

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Every structure of UniProt A0A348FUE1
Elsewhere: RCSB PDB 7S09 · PDBe 7S09 · UniProt A0A348FUE1

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