Research workbench
Crystal structure of fbf-2 in complex with lst-1 site a peptide and compact fbe RNA
Analyse Crystal structure of fbf-2 in complex with lst-1 site a peptide and compact fbe… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7RZZ
- Type
- protein + RNA
- Length
- 417 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fem-3 mRNA-binding factor 2; RNA; Lateral signaling target
- UniProt
- Q09312, P91820
- Pockets
- 2 · best druggability 0.37
Structure
x-ray diffraction · 3 distinct chains · 68% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fem-3 mRNA-binding factor 2 | protein | 394 | 71% helix, 1% strand | Q09312 |
| B | RNA | rna | 8 | — | — |
| C | Lateral signaling target | protein | 15 | 0% helix, 7% strand | P91820 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 74 | 0.37 | 0.77 | 15 | empty |
| 2 | 55 | 0.31 | 0.76 | 13 | empty |
Interfaces
2 interfaces between chains.
- A–B · 1415 Ų buried · 52 hydrogen bonds · protein-nucleic
- A–C · 777 Ų buried · 11 hydrogen bonds · protein-protein
Compared structures
- 7RZZ · Crystal structure of FBF-2 in complex with LST-1 site A peptide and compact FBE RNA · the same entry in another collection · chain A against A, TM-score 1.00
- Q09312 · AlphaFold monomer V2.0 prediction for fem-3 mRNA-binding factor 2 (Q09312) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q09312
- Every structure of UniProt P91820
- Elsewhere: RCSB PDB 7RZZ · PDBe 7RZZ · UniProt Q09312 · UniProt P91820
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.