Research workbench
Crystal structure of btrk, a decarboxylase involved in butirosin biosynthesis
Analyse Crystal structure of btrk, a decarboxylase involved in butirosin biosynthesis in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7RU7
- Type
- protein
- Length
- 412 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- L-glutamyl-[btri acyl-carrier protein] decarboxylase
- EC
- 4.1.1.95
- UniProt
- Q2L4H3
- Ligands
- PLP
- Pockets
- 2 · best druggability 0.53
Structure
x-ray diffraction · 1 distinct chain · 36% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | L-glutamyl-[btri acyl-carrier protein] decarboxylase (EC 4.1.1.95) | protein | 412 | 36% helix, 25% strand | Q2L4H3 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 108 | 0.53 | 0.83 | 26 | PLP |
| 2 | 81 | 0.40 | 0.79 | 21 | empty |
Modifications
Observed in the structure: 1 cofactor (pyridoxal phosphate Schiff base).
Compared structures
- 7RU7 · Crystal structure of BtrK, a decarboxylase involved in butirosin biosynthesis · the same entry in another collection · chain A against A, TM-score 1.00
- Q2L4H3 · AlphaFold monomer V2.0 prediction for L-glutamyl-[btri acyl-carrier protein]… · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q2L4H3
- Elsewhere: RCSB PDB 7RU7 · PDBe 7RU7 · UniProt Q2L4H3
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