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Rat liver L-serine dehydratase apo enzyme
Analyse Rat liver L-serine dehydratase apo enzyme in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1PWE
- Type
- protein
- Length
- 1,890 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- L-serine dehydratase
- EC
- 4.3.1.17
- UniProt
- P09367
- Pockets
- 13 · best druggability 0.86
Structure
x-ray diffraction · 1 distinct chain · 47% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F | L-serine dehydratase (EC 4.3.1.17) | protein | 315 | 47% helix, 14% strand | P09367 |
Pockets
13 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1120 | 0.86 | 0.87 | 136 | empty |
| 2 | 1173 | 0.86 | 0.87 | 139 | empty |
| 3 | 1183 | 0.85 | 0.86 | 137 | empty |
| 4 | 279 | 0.51 | 0.74 | 38 | empty |
| 5 | 73 | 0.40 | 0.79 | 16 | empty |
Interfaces
6 interfaces between chains.
- C–D · 2506 Ų buried · 28 hydrogen bonds · protein-protein
- A–B · 2504 Ų buried · 28 hydrogen bonds · protein-protein
- E–F · 2486 Ų buried · 29 hydrogen bonds · protein-protein
- A–F · 326 Ų buried · 4 hydrogen bonds · protein-protein
- D–E · 79 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P09367
- Elsewhere: RCSB PDB 1PWE · PDBe 1PWE · UniProt P09367
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