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Crystal structure of triosephosphate isomerase from verrucomicrobium spinosum
Analyse Crystal structure of triosephosphate isomerase from verrucomicrobium spinosum in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7RMN
- Type
- protein
- Length
- 533 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Triosephosphate isomerase
- EC
- 5.3.1.1
- Pockets
- 5 · best druggability 0.57
Structure
x-ray diffraction · 2 distinct chains · 46% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Triosephosphate isomerase (EC 5.3.1.1) | protein | 268 | 45% helix, 14% strand | — |
| B | Triosephosphate isomerase (EC 5.3.1.1) | protein | 265 | 46% helix, 14% strand | — |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 87 | 0.57 | 0.87 | 20 | empty |
| 2 | 91 | 0.45 | 0.80 | 22 | empty |
| 3 | 72 | 0.42 | 0.80 | 17 | empty |
| 4 | 96 | 0.42 | 0.78 | 25 | empty |
| 5 | 94 | 0.41 | 0.78 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 1627 Ų buried · 31 hydrogen bonds · protein-protein
Compared structures
- 7RMN · Crystal structure of triosephosphate isomerase from Verrucomicrobium spinosum · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 7RMN · PDBe 7RMN
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