Research workbench

Crystal structure of S. cerevisiae pre-mRNA leakage protein 39 (PML39)

Analyse Crystal structure of S. cerevisiae pre-mRNA leakage protein 39 (PML39) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7RDN
Type: protein
Length: 215 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Pre-mRNA leakage protein 39
UniProt: Q03760
Ligands: ZN
Pockets: 3 · best druggability 0.37

Structure

x-ray diffraction · 1 distinct chain · 43% helix, 11% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Pre-mRNA leakage protein 39	protein	215	43% helix, 11% strand	Q03760

Ligands and binding sites

ZN · Zinc ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	94	0.37	0.75	20	empty
2	85	0.33	0.73	16	empty
3	51	0.28	0.75	19	empty

Compared structures

7RDN · Crystal structure of S. cerevisiae pre-mRNA leakage protein 39 (Pml39) · the same entry in another collection · chain A against A, TM-score 1.00
Q03760 · AlphaFold monomer V2.0 prediction for pre-mRNA leakage protein 39 (Q03760) · a predicted model of the same protein · chain A against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q03760
Elsewhere: RCSB PDB 7RDN · PDBe 7RDN · UniProt Q03760

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.