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Structure of a cytosolic sulfotransferase of anopheles gambiae (AGAP001425).

Analyse Structure of a cytosolic sulfotransferase of anopheles gambiae (AGAP001425). in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7R0O
Type: protein
Length: 670 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: AGAP001425-pa
UniProt: Q7PXJ0
Ligands: CL
Pockets: 4 · best druggability 0.83

Structure

x-ray diffraction · 2 distinct chains · 50% helix, 11% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	AGAP001425-pa	protein	334	50% helix, 11% strand	Q7PXJ0
B	AGAP001425-pa	protein	336	51% helix, 11% strand	Q7PXJ0

Ligands and binding sites

CL · Chloride ion · ion · 2 copies · chains A, B
GOL · Glycerol · additive · 6 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1076	0.83	0.83	89	GOL
2	1174	0.82	0.83	108	GOL
3	518	0.66	0.78	60	empty
4	78	0.34	0.76	16	empty

Interfaces

1 interface between chains.

A–B · 1049 Å² buried · 25 hydrogen bonds · protein-protein

Compared structures

7R0O · Structure of a cytosolic sulfotransferase of Anopheles gambiae (AGAP001425). · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7PXJ0
Elsewhere: RCSB PDB 7R0O · PDBe 7R0O · UniProt Q7PXJ0

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