Research workbench
Crystal structure of the R270K mutant of aspartate semialdehyde dehydrogenase from haemophilus influenzae
Analyse Crystal structure of the R270K mutant of aspartate semialdehyde dehydrogenase… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1PS8
- Type
- protein
- Length
- 357 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Aspartate semialdehyde dehydrogenase
- EC
- 1.2.1.11
- UniProt
- P44801
- Pockets
- 1 · best druggability 0.59
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Aspartate semialdehyde dehydrogenase (EC 1.2.1.11) | protein | 357 | 41% helix, 23% strand | P44801 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 309 | 0.59 | 0.78 | 40 | empty |
Compared structures
- 1PS8 · Crystal Structure of the R270K Mutant of Aspartate Semialdehyde dehydrogenase from… · the same entry in another collection · chain A against A, TM-score 1.00
- P44801 · AlphaFold monomer V2.0 prediction for aspartate-semialdehyde dehydrogenase (P44801) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P44801
- Elsewhere: RCSB PDB 1PS8 · PDBe 1PS8 · UniProt P44801
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