Research workbench
Vaccinia virus E2
Analyse Vaccinia virus E2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7PHY
- Type
- protein
- Length
- 732 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein E2
- UniProt
- P21604
- Pockets
- 6 · best druggability 0.65
Structure
x-ray diffraction · 1 distinct chain · 59% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein E2 | protein | 732 | 59% helix, 5% strand | P21604 |
Ligands and binding sites
- GOL · Glycerol · additive · 5 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 52 | 0.65 | 0.95 | 15 | empty |
| 2 | 556 | 0.63 | 0.75 | 56 | empty |
| 3 | 348 | 0.58 | 0.76 | 37 | GOL |
| 4 | 55 | 0.41 | 0.82 | 18 | empty |
| 5 | 74 | 0.41 | 0.79 | 13 | empty |
Modifications
Observed in the structure: 1 disulfide, 1 modified (disulfide, nonstandard).
Compared structures
- 7PHY · Vaccinia virus E2 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P21604
- Elsewhere: RCSB PDB 7PHY · PDBe 7PHY · UniProt P21604
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