Research workbench
Crystal structure of the endoglucanase RBCEL1 E135Q
Analyse Crystal structure of the endoglucanase RBCEL1 E135Q in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7P6G
- Type
- protein
- Length
- 638 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Endoglucanase
- EC
- 3.2.1.4
- UniProt
- C1JI15
- Pockets
- 4 · best druggability 0.78
Structure
x-ray diffraction · 2 distinct chains · 36% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Endoglucanase (EC 3.2.1.4) | protein | 320 | 36% helix, 16% strand | C1JI15 |
| B | Endoglucanase (EC 3.2.1.4) | protein | 318 | 36% helix, 16% strand | C1JI15 |
Ligands and binding sites
- TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol · additive · 2 copies · chains A, B
- EDO · 1,2-ethanediol · additive · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1021 | 0.78 | 0.80 | 76 | TRS |
| 2 | 213 | 0.47 | 0.74 | 35 | empty |
| 3 | 145 | 0.45 | 0.76 | 28 | TRS |
| 4 | 64 | 0.30 | 0.75 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 555 Ų buried · 8 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 7P6G · Crystal structure of the endoglucanase RBcel1 E135Q · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C1JI15
- Elsewhere: RCSB PDB 7P6G · PDBe 7P6G · UniProt C1JI15
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.