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The crystal structure of a DNA:RNA hybrid duplex sequence cttttctttg with lna-amide modification

Analyse The crystal structure of a DNA:RNA hybrid duplex sequence cttttctttg with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
7OZZ
Type
DNA + RNA
Length
19 nucleotides
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
RNA (5'-R(*CP*AP*AP*AP*GP*AP*AP*AP*AP*G)-3'); DNA…
Ligands
K

Structure

x-ray diffraction · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
ARNA (5'-R(*CP*AP*AP*AP*GP*AP*AP*AP*AP*G)-3')rna10——
BDNA (5'-D(*CP*TP*(RWR)P*TP*CP*TP*TP*TP*G)-3')dna9——

Ligands and binding sites

  • K · Potassium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

  • A–B · 480 Ų buried · 50 hydrogen bonds · nucleic-nucleic

Modifications

Observed in the structure: 1 modified (nucleotide modification).

Compared structures

  • 7OZZ · The crystal structure of a DNA:RNA hybrid duplex sequence CTTTTCTTTG with LNA-amide… · the same entry in another collection · chain A against A, TM-score 1.00

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