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Crystal structure of the vim-2 acquired metallo-beta-lactamase in complex with compound 14 (jmv-6931)

Analyse Crystal structure of the vim-2 acquired metallo-beta-lactamase in complex with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7OVH
Type: protein
Length: 232 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Metallo-beta-lactamase vim-2-like protein
UniProt: B8QIQ9
Ligands: UNL, ZN
Pockets: 1 · best druggability 0.52

Structure

x-ray diffraction · 1 distinct chain · 27% helix, 29% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Metallo-beta-lactamase vim-2-like protein	protein	232	27% helix, 29% strand	B8QIQ9

Ligands and binding sites

UNL · Unknown ligand · ligand · chains A
ZN · Zinc ion · metal · 3 copies · chains A
ACT · Acetate ion · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	186	0.52	0.78	21	UNL

Compared structures

7OVH · Crystal structure of the VIM-2 acquired metallo-beta-Lactamase in Complex with compound… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B8QIQ9
Elsewhere: RCSB PDB 7OVH · PDBe 7OVH · UniProt B8QIQ9

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