Research workbench
Structure of human pd-L1 in complex with macrocyclic inhibitor
Analyse Structure of human pd-L1 in complex with macrocyclic inhibitor in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7OUN
- Type
- protein
- Length
- 131 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Programmed cell death 1 ligand 1; Macrocyclic peptide
- UniProt
- Q9NZQ7
Structure
x-ray diffraction · 2 distinct chains · 9% helix, 47% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Programmed cell death 1 ligand 1 | protein | 117 | 10% helix, 48% strand | Q9NZQ7 |
| B | Macrocyclic peptide | protein | 14 | 0% helix, 43% strand | — |
Interfaces
1 interface between chains.
- A–B · 486 Ų buried · 4 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 7OUN · Structure of human PD-L1 in complex with macrocyclic inhibitor · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9NZQ7
- Elsewhere: RCSB PDB 7OUN · PDBe 7OUN · UniProt Q9NZQ7
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