Research workbench
Circular permutant of ribosomal protein S6, swap helix 2, L75A, A92K mutant
Analyse Circular permutant of ribosomal protein S6, swap helix 2, L75A, A92K mutant in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7OS7
- Type
- protein
- Length
- 206 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 30S ribosomal protein S6,30S ribosomal protein S6
- UniProt
- Q5SLP8
- Pockets
- 2 · best druggability 0.40
Structure
x-ray diffraction · 2 distinct chains · 34% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 30S ribosomal protein S6,30S ribosomal protein S6 | protein | 105 | 33% helix, 43% strand | Q5SLP8 |
| B | 30S ribosomal protein S6,30S ribosomal protein S6 | protein | 101 | 35% helix, 45% strand | Q5SLP8 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 60 | 0.40 | 0.81 | 19 | empty |
| 2 | 57 | 0.38 | 0.80 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 929 Ų buried · 14 hydrogen bonds · protein-protein
Compared structures
- 7OS7 · Circular permutant of ribosomal protein S6, swap helix 2, L75A, A92K mutant · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5SLP8
- Elsewhere: RCSB PDB 7OS7 · PDBe 7OS7 · UniProt Q5SLP8
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