Research workbench
Crystal structure of C-terminally truncated bacillus subtilis nucleoid occlusion protein (noc) complexed to the noc-binding site (nbs)
Analyse Crystal structure of C-terminally truncated bacillus subtilis nucleoid… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7OL9
- Type
- protein + DNA
- Length
- 436 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nucleoid occlusion protein; DNA (5'-D(*TP*AP*TP*TP*TP*CP*CP*CP*GP*GP*GP*AP*AP*AP*TP*A)…
- UniProt
- P37524
- Pockets
- 6 · best druggability 0.73
Structure
x-ray diffraction · 3 distinct chains · 57% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nucleoid occlusion protein | protein | 201 | 57% helix, 11% strand | P37524 |
| B | Nucleoid occlusion protein | protein | 203 | 57% helix, 11% strand | P37524 |
| C, D | DNA (5'-D(*TP*AP*TP*TP*TP*CP*CP*CP*GP*GP*GP*AP*AP*AP*TP*A)- 3') | dna | 16 | — | — |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 781 | 0.73 | 0.78 | 73 | empty |
| 2 | 92 | 0.49 | 0.82 | 15 | empty |
| 3 | 97 | 0.46 | 0.80 | 13 | empty |
| 4 | 88 | 0.45 | 0.81 | 20 | empty |
| 5 | 98 | 0.35 | 0.73 | 21 | empty |
Interfaces
6 interfaces between chains.
- A–B · 1247 Ų buried · 9 hydrogen bonds · protein-protein
- C–D · 657 Ų buried · 57 hydrogen bonds · nucleic-nucleic
- B–D · 483 Ų buried · 14 hydrogen bonds · protein-nucleic
- A–C · 474 Ų buried · 14 hydrogen bonds · protein-nucleic
- B–C · 455 Ų buried · 9 hydrogen bonds · protein-nucleic
Compared structures
- 7OL9 · Crystal structure of C-terminally truncated Bacillus subtilis nucleoid occlusion protein… · the same entry in another collection · chain A against A, TM-score 1.00
- P37524 · AlphaFold monomer V2.0 prediction for nucleoid occlusion protein (P37524) · a predicted model of the same protein · chain B against A, TM-score 0.54
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P37524
- Elsewhere: RCSB PDB 7OL9 · PDBe 7OL9 · UniProt P37524
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