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The X-ray structure of L-threonine dehydrogenase from the common hospital pathogen clostridium difficile.

Analyse The X-ray structure of L-threonine dehydrogenase from the common hospital… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7OL1
Type: protein
Length: 638 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: L-threonine 3-dehydrogenase
EC: 1.1.1.103
UniProt: A0A346VYB9
Pockets: 5 · best druggability 0.74

Structure

x-ray diffraction · 1 distinct chain · 44% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	L-threonine 3-dehydrogenase (EC 1.1.1.103)	protein	319	44% helix, 15% strand	A0A346VYB9

Pockets

5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	558	0.74	0.81	57	empty
2	414	0.73	0.84	46	empty
3	167	0.50	0.78	23	empty
4	156	0.49	0.78	26	empty
5	54	0.27	0.74	16	empty

Interfaces

1 interface between chains.

A–B · 1339 Å² buried · 12 hydrogen bonds · protein-protein

Compared structures

7OL1 · The X-ray structure of L-threonine dehydrogenase from the common hospital pathogen… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A346VYB9
Elsewhere: RCSB PDB 7OL1 · PDBe 7OL1 · UniProt A0A346VYB9

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