Research workbench
Hepatitis B core protein mutant L60V + gsllgrmkga
Analyse Hepatitis B core protein mutant L60V + gsllgrmkga in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7OD8
- Type
- protein
- Length
- 593 residues
- Chains
- 6
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Capsid protein; Peptide gsllgrmkga
- UniProt
- P03146
- Pockets
- 10 · best druggability 0.77
Structure
electron microscopy · 4 distinct chains · 65% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Capsid protein | protein | 150 | 64% helix, 1% strand | P03146 |
| A | Capsid protein | protein | 143 | 68% helix, 0% strand | P03146 |
| C, D | Capsid protein | protein | 144 | 67% helix, 1% strand | P03146 |
| E, F | Peptide gsllgrmkga | protein | 6 | 0% helix, 0% strand | — |
Pockets
10 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 158 | 0.77 | 0.93 | 28 | empty |
| 2 | 149 | 0.70 | 0.89 | 32 | empty |
| 3 | 110 | 0.69 | 0.91 | 20 | empty |
| 4 | 105 | 0.67 | 0.90 | 20 | empty |
| 5 | 66 | 0.66 | 0.94 | 18 | empty |
Interfaces
7 interfaces between chains.
- B–A · 1979 Ų buried · 11 hydrogen bonds · protein-protein
- C–D · 1949 Ų buried · 13 hydrogen bonds · protein-protein
- B–C · 1009 Ų buried · 19 hydrogen bonds · protein-protein
- D–E · 243 Ų buried · 8 hydrogen bonds · protein-protein
- A–F · 219 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
- 7OD8 · Hepatitis B core Protein mutant L60V + GSLLGRMKGA · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03146
- Elsewhere: RCSB PDB 7OD8 · PDBe 7OD8 · UniProt P03146
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.