Research workbench
Hepatitis B core protein -low secretion phenotype P5T
Analyse Hepatitis B core protein -low secretion phenotype P5T in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7OCW
- Type
- protein
- Length
- 591 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Capsid protein
- UniProt
- A0A0U2YCX5
- Pockets
- 8 · best druggability 0.76
Structure
electron microscopy · 3 distinct chains · 67% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B, D | Capsid protein | protein | 151 | 63% helix, 1% strand | A0A0U2YCX5 |
| A | Capsid protein | protein | 143 | 71% helix, 0% strand | A0A0U2YCX5 |
| C | Capsid protein | protein | 146 | 68% helix, 1% strand | A0A0U2YCX5 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 140 | 0.76 | 0.94 | 28 | empty |
| 2 | 86 | 0.56 | 0.86 | 23 | empty |
| 3 | 85 | 0.54 | 0.85 | 14 | empty |
| 4 | 60 | 0.48 | 0.84 | 18 | empty |
| 5 | 90 | 0.47 | 0.80 | 17 | empty |
Interfaces
3 interfaces between chains.
- C–D · 2055 Ų buried · 10 hydrogen bonds · protein-protein
- B–A · 2051 Ų buried · 14 hydrogen bonds · protein-protein
- B–C · 1107 Ų buried · 12 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 7OCW · Hepatitis B core protein -low secretion phenotype P5T · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0U2YCX5
- Elsewhere: RCSB PDB 7OCW · PDBe 7OCW · UniProt A0A0U2YCX5
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