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C2 domain from protein kinase C delta

Analyse C2 domain from protein kinase C delta in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1BDY
Type: protein
Length: 246 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein kinase C
EC: 2.7.1.37
UniProt: P09215
Pockets: 2 · best druggability 0.57

Structure

x-ray diffraction · 1 distinct chain · 10% helix, 54% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Protein kinase C (EC 2.7.1.37)	protein	123	10% helix, 54% strand	P09215

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	279	0.57	0.77	39	empty
2	96	0.42	0.79	17	empty

Interfaces

1 interface between chains.

A–B · 756 Å² buried · 13 hydrogen bonds · protein-protein

Compared structures

1BDY · C2 domain from protein kinase C delta · the same entry in another collection · chain A against A, TM-score 1.00
P09215 · AlphaFold monomer V2.0 prediction for protein kinase C delta type (P09215) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P09215
Elsewhere: RCSB PDB 1BDY · PDBe 1BDY · UniProt P09215

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