Research workbench
Crystal structure of the mei-P26 nhl domain
Analyse Crystal structure of the mei-P26 nhl domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7NYQ
- Type
- protein
- Length
- 549 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Meiotic P26, isoform C
- UniProt
- M9PH32
- Pockets
- 4 · best druggability 0.74
Structure
x-ray diffraction · 2 distinct chains · 3% helix, 49% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Meiotic P26, isoform C | protein | 273 | 2% helix, 50% strand | M9PH32 |
| B | Meiotic P26, isoform C | protein | 276 | 4% helix, 49% strand | M9PH32 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 311 | 0.74 | 0.86 | 45 | empty |
| 2 | 499 | 0.70 | 0.80 | 56 | empty |
| 3 | 295 | 0.63 | 0.80 | 42 | empty |
| 4 | 111 | 0.39 | 0.75 | 24 | empty |
Interfaces
1 interface between chains.
- A–B · 522 Ų buried · 7 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 7NYQ · Crystal structure of the Mei-P26 NHL domain · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt M9PH32
- Elsewhere: RCSB PDB 7NYQ · PDBe 7NYQ · UniProt M9PH32
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