Research workbench

Three-quartet C-KIT2 G-quadruplex stabilized by a pyrene conjugate

Analyse Three-quartet C-KIT2 G-quadruplex stabilized by a pyrene conjugate in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7NWD
Type: DNA
Length: 21 nucleotides
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: C-KIT2_PY1
Ligands: K
Pockets: 1 · best druggability 0.30

Structure

solution nmr · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	C-KIT2_PY1	dna	21	—	—

Ligands and binding sites

K · Potassium ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	67	0.30	0.75	10	empty

Modifications

Observed in the structure: 1 modified (nucleotide modification).

Compared structures

7NWD · Three-quartet c-kit2 G-quadruplex stabilized by a pyrene conjugate · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 7NWD · PDBe 7NWD

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