Research workbench
Crystal structure of the tir domain of human TLR1 (crystallised without ZN2+ ions)
Analyse Crystal structure of the tir domain of human TLR1 (crystallised without ZN2+… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7NUX
- Type
- protein
- Length
- 160 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Toll-like receptor 1
- EC
- 3.2.2.6
- UniProt
- Q15399
- Pockets
- 2 · best druggability 0.39
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Toll-like receptor 1 (EC 3.2.2.6) | protein | 160 | 41% helix, 15% strand | Q15399 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 88 | 0.39 | 0.77 | 17 | empty |
| 2 | 90 | 0.36 | 0.75 | 18 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 7NUX · Crystal structure of the TIR domain of human TLR1 (crystallised without ZN2+ ions) · the same entry in another collection · chain A against A, TM-score 1.00
- Q15399 · AlphaFold monomer V2.0 prediction for toll-like receptor 1 (Q15399) · a predicted model of the same protein · chain A against A, TM-score 0.90
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q15399
- Elsewhere: RCSB PDB 7NUX · PDBe 7NUX · UniProt Q15399
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.