Research workbench
Rhinovirus-14 icam-1 empty particle at pH 6.2
Analyse Rhinovirus-14 icam-1 empty particle at pH 6.2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7NUM
- Type
- protein
- Length
- 520 residues
- Chains
- 3
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Genome polyprotein; P1
- EC
- 3.4.22.29, 3.6.1.15, 3.4.22.28, 2.7.7.48
- UniProt
- P03303
- Pockets
- 5 · best druggability 0.49
Structure
electron microscopy · 3 distinct chains · 11% helix, 39% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| 1 | Genome polyprotein (EC 3.4.22.29, 3.6.1.15, 3.4.22.28, 2.7.7.48) | protein | 155 | 7% helix, 45% strand | P03303 |
| 3 | P1 | protein | 197 | 12% helix, 30% strand | P03303 |
| 2 | Genome polyprotein (EC 3.4.22.29, 3.6.1.15, 3.4.22.28, 2.7.7.48) | protein | 168 | 13% helix, 44% strand | P03303 |
Pockets
5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 218 | 0.49 | 0.75 | 25 | empty |
| 2 | 60 | 0.45 | 0.83 | 16 | empty |
| 3 | 81 | 0.45 | 0.81 | 22 | empty |
| 4 | 103 | 0.43 | 0.78 | 16 | empty |
| 5 | 92 | 0.37 | 0.75 | 22 | empty |
Interfaces
3 interfaces between chains.
- 1–3 · 1877 Ų buried · 18 hydrogen bonds · protein-protein
- 3–2 · 1136 Ų buried · 14 hydrogen bonds · protein-protein
- 1–2 · 538 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
- 7NUM · Rhinovirus-14 ICAM-1 empty particle at pH 6.2 · the same entry in another collection · chain 1 against 1, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03303
- Elsewhere: RCSB PDB 7NUM · PDBe 7NUM · UniProt P03303
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