Research workbench
Rhinovirus-14 icam-1 activated particle at pH 6.2
Analyse Rhinovirus-14 icam-1 activated particle at pH 6.2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7NUL
- Type
- protein
- Length
- 519 residues
- Chains
- 3
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Genome polyprotein; P1
- EC
- 3.4.22.29, 3.6.1.15, 3.4.22.28, 2.7.7.48
- UniProt
- P03303
- Pockets
- 5 · best druggability 0.62
Structure
electron microscopy · 3 distinct chains · 11% helix, 42% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| 1 | Genome polyprotein (EC 3.4.22.29, 3.6.1.15, 3.4.22.28, 2.7.7.48) | protein | 155 | 12% helix, 48% strand | P03303 |
| 3 | P1 | protein | 199 | 11% helix, 32% strand | P03303 |
| 2 | Genome polyprotein (EC 3.4.22.29, 3.6.1.15, 3.4.22.28, 2.7.7.48) | protein | 165 | 11% helix, 48% strand | P03303 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 104 | 0.62 | 0.88 | 16 | empty |
| 2 | 93 | 0.48 | 0.81 | 24 | empty |
| 3 | 54 | 0.46 | 0.85 | 16 | empty |
| 4 | 89 | 0.37 | 0.75 | 18 | empty |
| 5 | 90 | 0.33 | 0.73 | 13 | empty |
Interfaces
3 interfaces between chains.
- 1–3 · 1884 Ų buried · 23 hydrogen bonds · protein-protein
- 3–2 · 1150 Ų buried · 10 hydrogen bonds · protein-protein
- 1–2 · 500 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 7NUL · Rhinovirus-14 ICAM-1 activated particle at pH 6.2 · the same entry in another collection · chain 1 against 1, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03303
- Elsewhere: RCSB PDB 7NUL · PDBe 7NUL · UniProt P03303
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