Research workbench
Cryo-EM structure of VAR2CSA FCR3 domain DBL5/6
Analyse Cryo-EM structure of VAR2CSA FCR3 domain DBL5/6 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7NNH
- Type
- protein
- Length
- 637 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Erythrocyte membrane protein 1
- UniProt
- Q6UDW7
- Pockets
- 16 · best druggability 0.74
Structure
electron microscopy · 1 distinct chain · 43% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| X | Erythrocyte membrane protein 1 | protein | 637 | 43% helix, 0% strand | Q6UDW7 |
Pockets
16 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 89 | 0.74 | 0.96 | 27 | empty |
| 2 | 211 | 0.70 | 0.87 | 28 | empty |
| 3 | 143 | 0.66 | 0.87 | 24 | empty |
| 4 | 256 | 0.61 | 0.80 | 38 | empty |
| 5 | 191 | 0.55 | 0.79 | 24 | empty |
Modifications
Observed in the structure: 9 disulfide (disulfide).
Compared structures
- 7NNH · Cryo-EM structure of VAR2CSA FCR3 domain DBL5/6 · the same entry in another collection · chain X against X, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6UDW7
- Elsewhere: RCSB PDB 7NNH · PDBe 7NNH · UniProt Q6UDW7
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