Research workbench
Crystal structure of fructose-bisphosphate aldolases fbac from bacillus methanolicus
Analyse Crystal structure of fructose-bisphosphate aldolases fbac from bacillus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7NC7
- Type
- protein
- Length
- 545 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fructose-bisphosphate aldolase
- EC
- 4.1.2.13
- UniProt
- I3EBM6
- Ligands
- 13P
- Pockets
- 2 · best druggability 0.48
Structure
x-ray diffraction · 2 distinct chains · 52% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fructose-bisphosphate aldolase (EC 4.1.2.13) | protein | 273 | 51% helix, 16% strand | I3EBM6 |
| B | Fructose-bisphosphate aldolase (EC 4.1.2.13) | protein | 272 | 52% helix, 17% strand | I3EBM6 |
Ligands and binding sites
- 13P · 1,3-dihydroxyacetonephosphate · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 175 | 0.48 | 0.77 | 33 | 13P |
| 2 | 128 | 0.44 | 0.77 | 24 | 13P |
Interfaces
1 interface between chains.
- A–B · 1760 Ų buried · 34 hydrogen bonds · protein-protein
Compared structures
- 7NC7 · Crystal structure of fructose-bisphosphate aldolases FBAC from Bacillus methanolicus · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt I3EBM6
- Elsewhere: RCSB PDB 7NC7 · PDBe 7NC7 · UniProt I3EBM6
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