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Crystal structure of triosephosphate isomerase from candidatus prometheoarchaeum syntrophicum

Analyse Crystal structure of triosephosphate isomerase from candidatus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7N8U
Type: protein
Length: 530 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Triosephosphate isomerase
EC: 5.3.1.1
UniProt: A0A5B9DC34
Pockets: 3 · best druggability 0.48

Structure

x-ray diffraction · 2 distinct chains · 47% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Triosephosphate isomerase (EC 5.3.1.1)	protein	265	46% helix, 15% strand	A0A5B9DC34
B	Triosephosphate isomerase (EC 5.3.1.1)	protein	265	48% helix, 15% strand	A0A5B9DC34

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	155	0.48	0.77	31	empty
2	129	0.47	0.78	28	empty
3	85	0.43	0.80	23	empty

Interfaces

1 interface between chains.

A–B · 1722 Å² buried · 32 hydrogen bonds · protein-protein

Compared structures

7N8U · Crystal structure of Triosephosphate isomerase from Candidatus Prometheoarchaeum… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A5B9DC34
Elsewhere: RCSB PDB 7N8U · PDBe 7N8U · UniProt A0A5B9DC34

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