Research workbench
Solution structure of the tissue-type plasminogen activator kringle 2 domain complexed to 6-aminohexanoic acid an antifibrinolytic drug
Analyse Solution structure of the tissue-type plasminogen activator kringle 2 domain… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1PK2
- Type
- protein
- Length
- 90 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tissue-type plasminogen activator
- EC
- 3.4.21.68
- UniProt
- P00750
- Ligands
- ACA
Structure
solution nmr · 1 distinct chain · 8% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tissue-type plasminogen activator (EC 3.4.21.68) | protein | 90 | 8% helix, 19% strand | P00750 |
Ligands and binding sites
- ACA · 6-aminohexanoic acid · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Modifications
Observed in the structure: 3 disulfide (disulfide).
Compared structures
- 1PK2 · Solution structure of the tissue-type plasminogen activator kringle 2 domain complexed to… · the same entry in another collection · chain A against A, TM-score 1.00
- P00750 · AlphaFold monomer V2.0 prediction for tissue-type plasminogen activator (P00750) · a predicted model of the same protein · chain A against A, TM-score 0.80
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00750
- Elsewhere: RCSB PDB 1PK2 · PDBe 1PK2 · UniProt P00750
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