Research workbench

Crystal structure of ricin a chain in complex with 5-(2-ethylphenyl) thiophene-2-carboxylic acid

Analyse Crystal structure of ricin a chain in complex with 5-(2-ethylphenyl)… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7MLT
Type: protein
Length: 256 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ricin
EC: 3.2.2.22
UniProt: P02879
Ligands: ZJD, CL
Pockets: 2 · best druggability 0.57

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ricin (EC 3.2.2.22)	protein	256	40% helix, 18% strand	P02879

Ligands and binding sites

ZJD · 5-(2-ethylphenyl)thiophene-2-carboxylic acid · ligand · chains A
CL · Chloride ion · ion · 3 copies · chains A
EDO · 1,2-ethanediol · additive · 18 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	272	0.57	0.78	35	EDO
2	57	0.33	0.77	19	empty

Compared structures

7MLT · Crystal structure of ricin A chain in complex with… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P02879
Elsewhere: RCSB PDB 7MLT · PDBe 7MLT · UniProt P02879

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.