Research workbench
SIALIDASE24 apo
Analyse SIALIDASE24 apo in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7MHU
- Type
- protein
- Length
- 748 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Exo-alpha-sialidase
- UniProt
- A0A4S2B3K9
- Pockets
- 6 · best druggability 0.73
Structure
x-ray diffraction · 1 distinct chain · 2% helix, 48% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Exo-alpha-sialidase | protein | 374 | 2% helix, 48% strand | A0A4S2B3K9 |
Pockets
6 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 700 | 0.73 | 0.79 | 83 | empty |
| 2 | 269 | 0.68 | 0.84 | 33 | empty |
| 3 | 288 | 0.66 | 0.82 | 31 | empty |
| 4 | 284 | 0.56 | 0.77 | 47 | empty |
| 5 | 289 | 0.56 | 0.77 | 46 | empty |
Interfaces
1 interface between chains.
- A–B · 404 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 7MHU · Sialidase24 apo · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A4S2B3K9
- Elsewhere: RCSB PDB 7MHU · PDBe 7MHU · UniProt A0A4S2B3K9
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