Research workbench
T4GALA engineered protein nanocage
Analyse T4GALA engineered protein nanocage in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7MH2
- Type
- protein
- Length
- 1,114 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- T4GALA engineered protein nanocage
- UniProt
- A0A0F5HPP7
- Pockets
- 15 · best druggability 0.83
Structure
electron microscopy · 2 distinct chains · 30% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C | T4GALA engineered protein nanocage | protein | 278 | 29% helix, 24% strand | A0A0F5HPP7 |
| B, D | T4GALA engineered protein nanocage | protein | 279 | 31% helix, 27% strand | A0A0F5HPP7 |
Pockets
15 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 985 | 0.83 | 0.85 | 87 | empty |
| 2 | 1080 | 0.80 | 0.81 | 97 | empty |
| 3 | 58 | 0.61 | 0.92 | 14 | empty |
| 4 | 238 | 0.53 | 0.76 | 31 | empty |
| 5 | 252 | 0.52 | 0.76 | 25 | empty |
Interfaces
5 interfaces between chains.
- B–C · 1733 Ų buried · 14 hydrogen bonds · protein-protein
- C–D · 1609 Ų buried · 12 hydrogen bonds · protein-protein
- A–D · 457 Ų buried · 1 hydrogen bond · protein-protein
- A–C · 181 Ų buried · 0 hydrogen bonds · protein-protein
- A–B · 137 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 7MH2 · T4GALA Engineered Protein Nanocage · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0F5HPP7
- Elsewhere: RCSB PDB 7MH2 · PDBe 7MH2 · UniProt A0A0F5HPP7
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