Research workbench
Outward facing conformation of the metni methionine ABC transporter in complex with lipo-metq
Analyse Outward facing conformation of the metni methionine ABC transporter in complex… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7MBZ
- Type
- protein
- Length
- 1,172 residues
- Chains
- 5
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- ABC transporter, permease protein; Lipoprotein; ABC transporter, ATP-binding protein
- UniProt
- Q9JXP3, Q7DD63, Q9JXP2
- Pockets
- 16 · best druggability 0.87
Structure
electron microscopy · 4 distinct chains · 48% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | ABC transporter, permease protein | protein | 222 | 84% helix, 0% strand | Q9JXP3 |
| E | Lipoprotein | protein | 241 | 38% helix, 22% strand | Q7DD63 |
| C | ABC transporter, ATP-binding protein | protein | 242 | 38% helix, 19% strand | Q9JXP2 |
| D | ABC transporter, ATP-binding protein | protein | 245 | 34% helix, 20% strand | Q9JXP2 |
Pockets
16 pockets found on a 1 Å grid, 10 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1009 | 0.87 | 0.88 | 133 | empty |
| 2 | 1162 | 0.85 | 0.85 | 140 | empty |
| 3 | 941 | 0.83 | 0.85 | 129 | empty |
| 4 | 159 | 0.77 | 0.93 | 35 | empty |
| 5 | 677 | 0.77 | 0.82 | 94 | empty |
Interfaces
6 interfaces between chains.
- A–B · 1702 Ų buried · 10 hydrogen bonds · protein-protein
- C–D · 1306 Ų buried · 21 hydrogen bonds · protein-protein
- E–B · 953 Ų buried · 14 hydrogen bonds · protein-protein
- B–D · 862 Ų buried · 7 hydrogen bonds · protein-protein
- A–C · 826 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
- 7MBZ · Outward facing conformation of the MetNI methionine ABC transporter in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9JXP3
- Every structure of UniProt Q7DD63
- Every structure of UniProt Q9JXP2
- Elsewhere: RCSB PDB 7MBZ · PDBe 7MBZ · UniProt Q9JXP3 · UniProt Q7DD63 · UniProt Q9JXP2
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