Research workbench
Canine parvovirus and FAB14 asymmetric reconstruction
Analyse Canine parvovirus and FAB14 asymmetric reconstruction in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7M3N
- Type
- protein
- Length
- 759 residues
- Chains
- 3
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cpv FAB14 light chain; Cpv FAB14 heavy chain; Capsid protein 2
- UniProt
- B2ZG07
- Pockets
- 12 · best druggability 0.64
Structure
electron microscopy · 3 distinct chains · 6% helix, 36% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| L | Cpv FAB14 light chain | protein | 108 | 0% helix, 50% strand | — |
| H | Cpv FAB14 heavy chain | protein | 119 | 3% helix, 43% strand | — |
| A | Capsid protein 2 | protein | 532 | 8% helix, 31% strand | B2ZG07 |
Pockets
12 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 253 | 0.64 | 0.82 | 46 | empty |
| 2 | 378 | 0.58 | 0.75 | 44 | empty |
| 3 | 416 | 0.56 | 0.74 | 36 | empty |
| 4 | 174 | 0.52 | 0.79 | 26 | empty |
| 5 | 68 | 0.41 | 0.80 | 23 | empty |
Interfaces
3 interfaces between chains.
- L–H · 828 Ų buried · 7 hydrogen bonds · protein-protein
- H–A · 422 Ų buried · 3 hydrogen bonds · protein-protein
- L–A · 219 Ų buried · 6 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 3 disulfide (disulfide).
Compared structures
- 7M3N · Canine parvovirus and Fab14 asymmetric reconstruction · the same entry in another collection · chain L against L, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B2ZG07
- Elsewhere: RCSB PDB 7M3N · PDBe 7M3N · UniProt B2ZG07
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