Research workbench

Structural and biochemical insight into assembly of molecular motors involved in viral DNA packaging

Analyse Structural and biochemical insight into assembly of molecular motors involved… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7LXS
Type: protein
Length: 440 residues
Chains: 8
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Terminase, small subunit
Pockets: 2 · best druggability 0.66

Structure

x-ray diffraction · 1 distinct chain · 51% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D, E, F, G, H	Terminase, small subunit	protein	55	51% helix, 13% strand	—

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	699	0.66	0.75	74	empty
2	186	0.53	0.78	30	empty

Interfaces

15 interfaces between chains.

E–H · 578 Å² buried · 6 hydrogen bonds · protein-protein
A–C · 575 Å² buried · 6 hydrogen bonds · protein-protein
A–E · 313 Å² buried · 3 hydrogen bonds · protein-protein
B–F · 287 Å² buried · 3 hydrogen bonds · protein-protein
A–B · 176 Å² buried · 2 hydrogen bonds · protein-protein

Compared structures

7LXS · Structural and Biochemical Insight into Assembly of Molecular Motors Involved in Viral… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 7LXS · PDBe 7LXS

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.