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Structural and biochemical insight into assembly of molecular motors involved in viral DNA packaging

Analyse Structural and biochemical insight into assembly of molecular motors involved… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7LWR
Type: protein
Length: 432 residues
Chains: 8
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Terminase, small subunit
UniProt: P68654
Pockets: 3 · best druggability 0.71

Structure

x-ray diffraction · 1 distinct chain · 48% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D, E, F, G, H	Terminase, small subunit	protein	54	48% helix, 13% strand	P68654

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	425	0.71	0.82	49	empty
2	168	0.45	0.75	30	empty
3	51	0.28	0.75	15	empty

Interfaces

13 interfaces between chains.

C–E · 604 Å² buried · 7 hydrogen bonds · protein-protein
B–F · 600 Å² buried · 5 hydrogen bonds · protein-protein
D–G · 592 Å² buried · 6 hydrogen bonds · protein-protein
C–F · 404 Å² buried · 3 hydrogen bonds · protein-protein
D–H · 334 Å² buried · 6 hydrogen bonds · protein-protein

Compared structures

7LWR · Structural and Biochemical Insight into Assembly of Molecular Motors Involved in Viral… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P68654
Elsewhere: RCSB PDB 7LWR · PDBe 7LWR · UniProt P68654

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