Research workbench
Bacterial cellulose synthase bcsb with polyalanine bcsa model
Analyse Bacterial cellulose synthase bcsb with polyalanine bcsa model in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7LBY
- Type
- protein
- Length
- 1,418 residues
- Chains
- 2
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cellulose synthase catalytic subunit [udp-forming]; Cyclic di-gmp-binding protein
- EC
- 2.4.1.12
- UniProt
- P37653, P37652
- Pockets
- 20 · best druggability 0.75
Structure
electron microscopy · 2 distinct chains · 36% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cellulose synthase catalytic subunit [udp-forming] (EC 2.4.1.12) | protein | 755 | 51% helix, 7% strand | P37653 |
| B | Cyclic di-gmp-binding protein | protein | 663 | 19% helix, 21% strand | P37652 |
Pockets
20 pockets found on a 1 Å grid, 10 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1143 | 0.75 | 0.78 | 113 | empty |
| 2 | 1060 | 0.72 | 0.75 | 98 | empty |
| 3 | 729 | 0.71 | 0.78 | 94 | empty |
| 4 | 236 | 0.67 | 0.84 | 27 | empty |
| 5 | 340 | 0.66 | 0.81 | 61 | empty |
Interfaces
1 interface between chains.
- A–B · 536 Ų buried · 1 hydrogen bond · protein-protein
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 7LBY · Bacterial cellulose synthase BcsB with polyalanine BcsA model · the same entry in another collection · chain A against A, TM-score 1.00
- P37652 · AlphaFold monomer V2.0 prediction for cyclic di-gmp-binding protein (P37652) · a predicted model of the same protein · chain B against A, TM-score 0.92
- P37653 · AlphaFold monomer V2.0 prediction for cellulose synthase catalytic subunit [udp-forming]… · a predicted model of the same protein · chain A against A, TM-score 0.84
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P37653
- Every structure of UniProt P37652
- Elsewhere: RCSB PDB 7LBY · PDBe 7LBY · UniProt P37653 · UniProt P37652
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.