Research workbench
Cryo-EM structure of HSP90:FKBP51:P23 closed-state complex
Analyse Cryo-EM structure of HSP90:FKBP51:P23 closed-state complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7L7I
- Type
- protein
- Length
- 1,775 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q13451, P07900, Q15185
- Ligands
- ANP
Structure
electron microscopy · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| C | — | protein | 409 | — | Q13451 |
| A, B | — | protein | 628 | — | P07900 |
| E | — | protein | 110 | — | Q15185 |
Ligands and binding sites
- ANP · Phosphoaminophosphonic acid-adenylate ester · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7L7I · Cryo-EM structure of Hsp90:FKBP51:p23 closed-state complex · the same entry in another collection · chain E against E, TM-score 1.00
- P07900 · AlphaFold monomer V2.0 prediction for heat shock protein HSP 90-alpha (P07900) · a predicted model of the same protein · chain A against A, TM-score 0.98
- Q15185 · AlphaFold monomer V2.0 prediction for prostaglandin E synthase 3 (Q15185) · a predicted model of the same protein · chain E against A, TM-score 0.97
- Q13451 · AlphaFold monomer V2.0 prediction for peptidyl-prolyl cis-trans isomerase FKBP5 (Q13451) · a predicted model of the same protein · chain C against A, TM-score 0.79
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13451
- Every structure of UniProt P07900
- Every structure of UniProt Q15185
- Elsewhere: RCSB PDB 7L7I · PDBe 7L7I · UniProt Q13451 · UniProt P07900 · UniProt Q15185
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