Research workbench
Molybdopterin cofactor biosynthesis protein E from burkholderia multivorans atcc 17616
Analyse Molybdopterin cofactor biosynthesis protein E from burkholderia multivorans… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7L2A
- Type
- protein
- Length
- 292 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Mpt synthase subunit 2
- EC
- 2.8.1.12
- UniProt
- A0A0H3KFN7
- Pockets
- 2 · best druggability 0.56
Structure
x-ray diffraction · 2 distinct chains · 33% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mpt synthase subunit 2 (EC 2.8.1.12) | protein | 146 | 34% helix, 32% strand | A0A0H3KFN7 |
| B | Mpt synthase subunit 2 (EC 2.8.1.12) | protein | 146 | 32% helix, 31% strand | A0A0H3KFN7 |
Ligands and binding sites
- EDO · 1,2-ethanediol · additive · 2 copies · chains A, B
- DMS · Dimethyl sulfoxide · additive · 2 copies · chains A, B
- IMD · Imidazole · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 238 | 0.56 | 0.78 | 26 | EDO, DMS |
| 2 | 276 | 0.55 | 0.76 | 26 | DMS, EDO |
Interfaces
1 interface between chains.
- A–B · 1470 Ų buried · 31 hydrogen bonds · protein-protein
Compared structures
- 7L2A · Molybdopterin cofactor biosynthesis protein E from Burkholderia multivorans ATCC 17616 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0H3KFN7
- Elsewhere: RCSB PDB 7L2A · PDBe 7L2A · UniProt A0A0H3KFN7
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