Research workbench

Zinc finger antiviral protein (zap) central domain

Analyse Zinc finger antiviral protein (zap) central domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7KZH
Type: protein
Length: 182 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Zinc finger ccch-type antiviral protein 1
UniProt: Q7Z2W4
Ligands: ZN
Pockets: 1 · best druggability 0.34

Structure

x-ray diffraction · 1 distinct chain · 20% helix, 36% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Zinc finger ccch-type antiviral protein 1	protein	182	20% helix, 36% strand	Q7Z2W4

Ligands and binding sites

ZN · Zinc ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	120	0.34	0.72	23	empty

Modifications

Observed in the structure: 5 modified (engineered).

Compared structures

7KZH · Zinc finger antiviral protein (ZAP) central domain · the same entry in another collection · chain A against A, TM-score 1.00
Q7Z2W4 · AlphaFold monomer V2.0 prediction for zinc finger ccch-type antiviral protein 1 (Q7Z2W4) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7Z2W4
Elsewhere: RCSB PDB 7KZH · PDBe 7KZH · UniProt Q7Z2W4

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.