Research workbench
Solution structures of full-length K-RAS bound to GDP
Analyse Solution structures of full-length K-RAS bound to GDP in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7KYZ
- Type
- protein
- Length
- 188 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Isoform 2B of GTPase KRAS
- EC
- 3.6.5.2
- UniProt
- P01116
- Pockets
- 3 · best druggability 0.50
Structure
solution nmr · 1 distinct chain · 38% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Isoform 2B of GTPase KRAS (EC 3.6.5.2) | protein | 188 | 38% helix, 21% strand | P01116 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 159 | 0.50 | 0.78 | 29 | empty |
| 2 | 69 | 0.34 | 0.76 | 13 | empty |
| 3 | 68 | 0.31 | 0.75 | 12 | empty |
Compared structures
- 7KYZ · Solution structures of full-length K-RAS bound to GDP · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P01116
- Elsewhere: RCSB PDB 7KYZ · PDBe 7KYZ · UniProt P01116
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