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Drosophila melanogaster long-chain fatty-acyl-CoA synthetase CG6178

Analyse Drosophila melanogaster long-chain fatty-acyl-CoA synthetase CG6178 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7KYD
Type: protein
Length: 534 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Long-chain fatty-acyl-CoA synthetase CG6178
EC: 6.2.1.3
UniProt: Q9VCC6
Ligands: C5Y
Pockets: 2 · best druggability 0.84

Structure

x-ray diffraction · 1 distinct chain · 32% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Long-chain fatty-acyl-CoA synthetase CG6178 (EC 6.2.1.3)	protein	534	32% helix, 27% strand	Q9VCC6

Ligands and binding sites

C5Y · 5'-O-[(S)-hydroxy(octanoyloxy)phosphoryl]adenosine · ligand · chains A
EDO · 1,2-ethanediol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1045	0.84	0.85	126	C5Y, EDO
2	248	0.60	0.79	33	empty

Compared structures

7KYD · Drosophila melanogaster long-chain fatty-acyl-CoA synthetase CG6178 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9VCC6
Elsewhere: RCSB PDB 7KYD · PDBe 7KYD · UniProt Q9VCC6

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