Research workbench
Adeno-associated virus serotype 5 in complex with the cellular receptor aavr at 2.5 ångströms resolution, AAV5 aavr
Analyse Adeno-associated virus serotype 5 in complex with the cellular receptor aavr at… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7KPN
- Type
- protein
- Length
- 604 residues
- Chains
- 2
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Dyslexia-associated protein KIAA0319-like protein; Capsid protein
- UniProt
- Q8IZA0, Q9YIJ1
- Pockets
- 6 · best druggability 0.67
Structure
electron microscopy · 2 distinct chains · 6% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| Z | Dyslexia-associated protein KIAA0319-like protein | protein | 88 | 0% helix, 42% strand | Q8IZA0 |
| A | Capsid protein | protein | 516 | 7% helix, 34% strand | Q9YIJ1 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 554 | 0.67 | 0.77 | 63 | empty |
| 2 | 314 | 0.56 | 0.76 | 45 | empty |
| 3 | 151 | 0.47 | 0.77 | 29 | empty |
| 4 | 220 | 0.47 | 0.74 | 32 | empty |
| 5 | 64 | 0.33 | 0.76 | 13 | empty |
Compared structures
- 7KPN · Adeno-associated virus serotype 5 in complex with the cellular receptor AAVR at 2.5… · the same entry in another collection · chain Z against Z, TM-score 1.00
- Q8IZA0 · AlphaFold monomer V2.0 prediction for dyslexia-associated protein KIAA0319-like protein… · a predicted model of the same protein · chain Z against A, TM-score 0.89
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8IZA0
- Every structure of UniProt Q9YIJ1
- Elsewhere: RCSB PDB 7KPN · PDBe 7KPN · UniProt Q8IZA0 · UniProt Q9YIJ1
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